The week in markets: S&P 500 Information Technology leads the week (+3.5%) · September 21–25, 2026

The trading week of September 21–25, 2026 in review: 75 of 95 tracked assets (79 %) finished the week higher, with the major equity indices moving +1.0 % on average over the week. This part focuses on equities and benchmark indices; crypto, commodities and FX follow on Sunday.
Weekly barometer
Weekly change = weekend close versus roughly five trading days earlier.
Indices over the week
Stocks: weekly gainers & losers
Gainers
| Name | Price | Change |
|---|---|---|
| GRAIL, Inc. GRAL | $126.89 | +58.71 % |
| Alamos Gold Inc. AGI | $34.5 | +37.18 % |
| Moderna Inc. MRNA | $198.88 | +29.11 % |
| Everpure, Inc. P | $126 | +20.99 % |
| Astera Labs Inc. ALAB | $364.62 | +20.24 % |
| Credo Technology Group Holding Ltd. CRDO | $210.97 | +19.94 % |
| Datadog Inc. Class A DDOG | $268.13 | +16.62 % |
| IonQ, Inc. IONQ | $45.48 | +16.23 % |
Losers
| Name | Price | Change |
|---|---|---|
| Gen Digital Inc. GEN | $21.62 | -25.47 % |
| Banzai International, Inc. PARA | $0.7 | -24.71 % |
| Cable One, Inc. CABO | $14.65 | -15.66 % |
| Nektar Therapeutics NKTR | $57.06 | -14.96 % |
| MGM Resorts International MGM | $32.58 | -13.83 % |
| Abivax SA ABVX | $91.06 | -13.31 % |
| Paychex Inc. PAYX | $101.37 | -12.72 % |
| Gildan Activewear Inc. GIL | $40.98 | -12.57 % |
From the US stocks Alysly charts. Weekly swings in single names can be far larger than those of the indices.




